John P Gaughan Selected Research

beta-adrenergic receptor kinase inhibitory peptide

6/2009	Right ventricular beneficial effects of beta adrenergic receptor kinase inhibitor (betaARKct) gene transfer in a rat model of severe pressure overload.
10/2008	Adenoviral beta-adrenergic receptor kinase inhibitor gene transfer improves exercise capacity, cardiac contractility, and systemic inflammation in a model of pressure overload hypertrophy.

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John P Gaughan Research Topics

Disease

12	Wounds and Injuries (Trauma) 01/2023 - 02/2007
8	Heart Failure 01/2016 - 08/2004
7	Neoplasms (Cancer) 11/2023 - 09/2004
6	Emphysema 04/2010 - 01/2005
5	Infections 11/2021 - 09/2006
4	Pulmonary Embolism 11/2021 - 04/2007
4	Hemorrhagic Shock 01/2018 - 05/2013
4	Hemorrhage 01/2018 - 08/2012
4	Shock 07/2014 - 08/2010
4	Inflammation (Inflammations) 11/2012 - 04/2008
3	Chronic Obstructive Pulmonary Disease (COPD) 04/2011 - 12/2008
3	Hypertrophy 05/2009 - 10/2008
2	Scoliosis 01/2022 - 01/2022
2	Venous Thromboembolism 01/2022 - 12/2017
2	Sepsis (Septicemia) 11/2021 - 09/2006
2	Pain (Aches) 01/2020 - 01/2019
2	Breast Neoplasms (Breast Cancer) 10/2018 - 06/2017
2	Triple Negative Breast Neoplasms 10/2018 - 06/2017
2	Venous Thrombosis (Deep-Vein Thrombosis) 12/2017 - 05/2012
2	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2016 - 11/2005
2	Hypothermia 05/2013 - 04/2012
2	Spinal Cord Injuries (Spinal Cord Injury) 01/2013 - 01/2007
2	Chronic Kidney Failure (Chronic Renal Failure) 11/2012 - 06/2010
2	Stress Fractures (Stress Fracture) 08/2011 - 05/2010
2	Pathologic Processes 06/2009 - 07/2004
2	Neoplasm Metastasis (Metastasis) 01/2007 - 09/2004
2	Hypertension (High Blood Pressure) 05/2006 - 01/2002
2	Lacerations 07/2005 - 04/2005
1	COVID-19 11/2022
1	Ovarian Neoplasms (Ovarian Cancer) 01/2022
1	Wound Infection (Wound Infections) 11/2021
1	Weight Loss (Weight Reduction) 11/2021
1	Adenocarcinoma 02/2021
1	Non-alcoholic Fatty Liver Disease 12/2020
1	Hematoma 10/2020
1	Seroma 10/2020
1	Postoperative Nausea and Vomiting (PONV) 01/2020
1	Migraine Disorders (Migraine) 01/2019
1	Diverticulitis 09/2018
1	Kidney Diseases (Kidney Disease) 09/2018
1	Hypovolemia 09/2018
1	Acute Kidney Injury (Acute Renal Failure) 09/2018

Drug/Important Bio-Agent (IBA)

3	Morphine (MS Contin)FDA LinkGeneric 01/2020 - 09/2003
3	CreatinineIBA 09/2018 - 01/2002
3	Oxygen (Dioxygen)IBA 07/2014 - 01/2003
3	Lactic Acid (Lactate)FDA LinkGeneric 07/2014 - 08/2012
2	Dihydrotachysterol (AT 10)IBA 01/2019 - 01/2007
2	Paclitaxel (Taxol)FDA LinkGeneric 10/2018 - 06/2017
2	Crystalloid SolutionsIBA 01/2018 - 01/2007
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2017 - 01/2016
2	vinyltriethoxysilane (VTES)IBA 12/2017 - 04/2007
2	Biomarkers (Surrogate Marker)IBA 04/2016 - 07/2004
2	Insulin (Novolin)FDA Link 01/2016 - 03/2013
2	LigandsIBA 11/2012 - 01/2007
2	Proteins (Proteins, Gene)FDA Link 11/2012 - 01/2007
2	beta-adrenergic receptor kinase inhibitory peptideIBA 06/2009 - 10/2008
2	CalciumIBA 06/2009 - 08/2004
1	Carbonyl Cyanide m-Chlorophenyl Hydrazone (CCCP)IBA 11/2023
1	Heparin (Liquaemin)FDA LinkGeneric 01/2022
1	AnticoagulantsIBA 01/2022
1	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 10/2020
1	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020
1	Opioid Analgesics (Opioids)IBA 01/2020
1	SolutionsIBA 01/2019
1	Saline SolutionIBA 01/2019
1	taxaneIBA 10/2018
1	SiliconesIBA 10/2018
1	Therapeutic UsesIBA 10/2018
1	Urea (Carbamide)FDA LinkGeneric 09/2018
1	NitrogenIBA 09/2018

Therapy/Procedure

9	Therapeutics 01/2022 - 06/2005
7	Length of Stay 01/2023 - 02/2007
7	Pneumonectomy (Lung Volume Reduction) 04/2010 - 01/2005
3	Neoadjuvant Therapy 01/2022 - 10/2018
3	Drug Therapy (Chemotherapy) 01/2022 - 10/2003
3	Resuscitation 01/2018 - 06/2010
3	Operative Surgical Procedures 12/2017 - 11/2004
3	Laparotomy 01/2017 - 04/2012
3	Transplantation 09/2010 - 03/2007
3	Surgical Instruments (Clip) 11/2005 - 04/2005
3	Episiotomy 11/2005 - 04/2005
2	Enhanced Recovery After Surgery 01/2020 - 09/2018
2	Contraindications 05/2017 - 01/2009
2	Activities of Daily Living (ADL) 01/2013 - 01/2007
2	Conservative Treatment 08/2011 - 05/2010
2	Heart Transplantation (Grafting, Heart) 06/2010 - 01/2009
2	Thoracotomy 12/2009 - 10/2008
2	Lung Transplantation 12/2009 - 01/2003
1	Terminal Care (Care, Terminal) 11/2022
1	Mechanical Ventilators (Ventilator) 01/2022
1	Spinal Fusion (Spondylosyndesis) 01/2022
1	Abdominoplasty 11/2021
1	Lithotripsy (Extracorporeal Shockwave Lithotripsy) 12/2020
1	Patient-Controlled Analgesia (Analgesia, Patient Controlled) 01/2020
1	Pain Management 01/2020
1	Fluid Therapy (Oral Rehydration Therapy) 01/2019
1	Mastectomy (Mammectomy) 10/2018
1	Segmental Mastectomy (Lumpectomy) 10/2018
1	Splints (Splint) 10/2018
1	General Anesthesia 10/2018